Hypoxaemia in wheezy infants after bronchodilator
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چکیده
The response of the bronchi to nebulised salbutamol was measured in five recurrently wheezy infants. Changes in oxygenation (measured by pulse oximeter and transcutaneous P02 electrodes) and carbon dioxide (measured by transcutaneous PCO2 electrode) were recorded at the same time. Neither nebulised saline nor salbutamol caused any changes in the measurements of airway function. A significant drop in mean oxygen saturation of 2% and of transcutaneous
منابع مشابه
Paradoxical response to nebulised salbutamol in wheezy infants, assessed by partial expiratory flow-volume curves.
Lower airway responses to nebulised bronchodilators were studied in 18 chronically or recurrently wheezy infants, aged 3-15 months, by means of partial forced expiratory flow-volume manoeuvres performed with an inflatable jacket. Maximum flow at functional residual capacity (FRC) (VmaxFRC) was used as the index of intrathoracic airways function. Peak expiratory flow rate was also measured. Base...
متن کاملEffect of bronchodilators on respiratory resisance in infants and young children with bronchiolitis and wheezy bronchitis.
Rutter, N., Milner, A. D., and Hiller, E. J. (1975). Archives of Disease in Childhood, 50, 719. Effect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis. Respiratory resistance was measured using a forced oscillation technique in 16 infants and young children with bronchiolitis and wheezy bronchitis. Measurements were made before...
متن کاملHypoxaemia after nebulised salbutamol in wheezy infants: the importance of aerosol acidity.
The effect of nebulised iso-osmolar, preservative free, but acidic salbutamol solution was studied in 34 acutely wheezing infants aged 1-17 months. Transcutaneous oxygen pressure (TcPO2) and oxygen saturation (SO2) fell significantly during the first five minutes after nebulisation with further deterioration at 15-20 minutes. Ten of these infants were followed up for another two hours and showe...
متن کاملLung function response to bronchodilator nebulization via hood in wheezy infants: a pilot study.
BACKGROUND In infants, small volume nebulizers with a face mask are commonly used to facilitate aerosol therapy. However, infants may be disturbed by mask application, causing poor mask-to-face seal and thus reducing the dose delivered. OBJECTIVES To compare lung function response to bronchodilator nebulization via two delivery devices: hood versus mask. METHODS We studied 26 recurrently wh...
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BACKGROUND Salbutamol is frequently used as a bronchodilator for infants who wheeze. Many single dose studies have questioned its effectiveness. AIMS To investigate the response of wheezy infants to salbutamol over an extended time period in order to elucidate either symptomatic relief or a protective effect. METHODS Eighty infants under 1 year, with persistent or recurrent wheeze and a per...
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